Vitamin D Reduces Mortality Rate among Kidney Patients

Kidney disease is one of the chronic diseases that affect human beings. About 40 million Americans are living with or at risk for chronic kidney disease (CKD). We know that Vitamin D deficiency causes rickets among children and osteoporosis among adults.
Vitamin D that we take as pills or receive through sunlight cannot be utilized if not activated. It is activated through two stages – liver and kidney. But people with kidney disease cannot make use of Vitamin D if taken in an inactivated form. Activated form of Vitamin D is available through prescriptions.

Activated Vitamin D for the last 30 years has been prescribed to kidney patients who had secondary hyperparathyroidism for suppressing parathyroid hormone level in blood

Vitamin D has other functions in the body apart from strengthening our bones and teeth. The body cannot absorb calcium if Vitamin D is deficient in the body. As Calcium and Phosphorus are required for healthy development of bones, Vitamins D facilitates the absorption of calcium in the body.

Activated form of vitamin D (calcitriol or 1,25 dihydroxy-vitamin D), which regulates absorption of calcium and phosphorus from foods, promotes formation of strong bone are often prescribed by physicians. Kidney patients experience brittleness of bones because their immune system weakens due to the increase of parathyroid hormones, which reduce calcium level in the blood.

Vitamin D when taken orally has been found that the parathyroid hormone level reduced in the blood and calcium level increased. Vitamin D is a facilitator for calcium absorption in the body and strengthens the bones and physical immunity. In kidney patients, who were administered activated Vitamin D showed reduced mortality risks. Some of them also escaped the chances of being put on dialysis as calcium intake also prevents deterioration of kidney functioning.

But researchers are still divided over the issue that Vitamin D reduces mortality risks in kidney patients. Consistent Vitamin D therapy did not always account for reduced mortality risks in kidney patients. In medical history some groups always shows positive signs of improvement on consuming certain types of medicine while the others may show signs of health deterioration after consuming the same medicine.

Remember that Vitamin D overdose can lead to the rise in level of calcitriol in the blood that is leading to the formation of kidney stones so one needs to be cautious with supplement intake and specially people with CKD should be cautious. They should rely strictly on their physician’s prescriptions to avoid further health complications.

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